Undercover Power of Endocannabinoids: Postsynaptic Ion-Channel Modulator
نویسندگان
چکیده
In this issue of Neuron, Gantz and Bean (2017) show that the endocannabinoid 2-arachidonoyl glycerol (2-AG) can directly alter the properties of native ion-channel Kv4.3 and accelerate the pacemaker activity of rodent dopamine neurons. These findings are one of the first demonstrations of postsynaptic, cell-autonomous actions of endocannabinoids in the mammalian brain.
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ورودعنوان ژورنال:
- Neuron
دوره 93 شماره
صفحات -
تاریخ انتشار 2017